Modifiers matching fate:

• unpleasant,
• same,
• differentiated,
• everyday,
• cellular,
• irreversible,
• specialized,
• catastrophic,
• developmental,
• horrible,

Simple categories matching irreversible:

• process,
• modification,
• disposal,
• event,
• trait,
• characteristic,
• behavior,
• action,
• condition,
• change,
• phenomenon,
• injury,
• cause,
• illness,
• abnormality,
• damage,
• disease,
• procedure,
• incident,
• dementia,
• means,
• thing,
• state,
• complication,
• reaction,
• disability,
• evolution,
• deformation,
• fate,