Modifiers matching manifestation:

• clinical,
• archival,
• physical,
• serious,
• severe,
• ischemic,
• underlying,
• supernatural,
• spiritual,
• external,
• physiological,
• cultural,
• public,
• extreme,
• neurologic,
• pathological,

Simple categories matching serious:

• attempt,
• sin,
• illness,
• disease,
• phobia,
• crime,
• title,
• condition,
• topic,
• operation,
• setback,
• occasion,
• flaw,
• infection,
• disaster,
• conduct,
• behavior,
• forum,
• contagion,
• disturbance,
• malfunction,
• offence,
• offense,
• reader,
• injury,
• act,
• disruption,
• drama,
• wound,
• disorder,
• pains,
• animal,
• pain,
• works,
• surgery,
• stage,
• harassment,
• status,
• form,
• user,
• misbehaviour,
• circumstances,
• song,
• procedure,
• infringement,
• passion,
• danger,
• mistake,
• nature,
• mishap,
• ailment,
• sector,
• issue,
• virus,
• bacteria,
• violence,
• participation,
• narcotic,
• program,
• dance,
• violation,
• development,
• misdeed,
• failure,
• point,
• activity,
• defect,
• work,
• infraction,
• theme,
• sanction,
• effort,
• action,
• complaint,
• emotion,
• endeavor,
• tendency,
• application,
• cancer,
• allergy,
• loss,
• enjoyment,
• zoonosis,
• item,
• trouble,
• consequence,
• music,
• morbidity,
• measure,
• stimulant,
• charge,
• wrongdoing,
• malignancy,
• evil,
• situation,
• accident,
• constraint,
• delinquent,
• addiction,
• tumour,
• handicap,
• material,
• matter,
• result,
• aberration,
• event,
• upheaval,
• gathering,
• malady,
• diversion,
• enterprise,
• system,
• study,
• imperfection,
• misconduct,
• intervention,
• difficulty,
• profession,
• writing,
• content,
• blemish,
• headache,
• threat,
• ceremony,
• subject,
• conflict,
• occurrence,
• abnormality,
• misfortune,
• incident,
• injustice,
• arrhythmia,
• storm,
• science,
• information,
• promise,
• case,
• hazard,
• drug,
• casualty,
• trait,
• cause,
• pathology,
• indiscipline,
• challenge,
• malpractice,
• reaction,
• abuse,
• entity,
• risk,
• disability,
• transgression,
• error,
• attack,
• state,
• experience,
• help,
• symptom,
• agent,
• phenomenon,
• story,
• journal,
• game,
• professional,
• assault,
• need,
• weapon,
• std,
• tale,
• substance,
• sickness,
• discipline,
• business,
• piece,
• stuff,
• interaction,
• idea,
• penalty,
• trauma,
• document,
• manifestation,
• larceny,
• problem,
• happening,
• damage,
• behaviour,
• thing,
• scholar,
• felony,
• complication,
• grounds,
• harm,
• pathogen,
• end,
• calamity,